PSYREFLECT

Issue #84

October 22, 2026

#1Research

A raised CRP in a client with depression

“An elevated CRP is a variable to bring to the client's physician, not a reason to promise that a drug will lift the mood.”

inflammationanhedoniadepressionC-reactive protein
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#2Research

In Adolescent Depression, Immune Markers Move in Both Directions

“In this adolescent sample, depression came with lower IL-6 and IL-10 and higher IL-17A, which is a change in balance and not a uniform rise in inflammation.”

adolescent depressioncytokinesTh17psychotic features
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#3Tool

A Short Checklist for Deciding Who Gets an Antibody Test in Psychosis

“A positive antibody result is a reason to ask more questions, not an answer to give the client.”

autoimmune psychosisantineuronal antibodiesNMDA receptorearly psychosis
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#4Industry

A German network sets out how to read antibody results in psychiatric patients

“A low-titer serum antibody is a reason to ask a second question, and the client should hear it that way.”

autoimmune encephalitisimmunopsychiatryantibody testingclinical recommendations
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#5Industry

Five factors a Russian review ties to persistent inflammation in psychiatric illness

“The review places these factors next to standard treatment, so what we can honestly offer a client is work alongside it, not a promise about inflammation.”

inflammationimmunopsychiatrychronic stressexercise
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#6Resource

Free neuroimmune case teaching for physicians, and what it means for your referrals

“A free, physician-only case consultation is useful to a psychologist as a question to put to the receiving psychiatrist, not as something to promise a client.”

Project ECHOneuroimmune psychiatryPANS/PANDASautoimmune encephalitis
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Issue #84 | PsyReflect