October 19, 2026
“A placebo arm with weekly visits and psychotherapy is a programme, and how quickly people leave it shows how they behave inside one.”
“Expected efficacy at baseline exceeded perceived efficacy at the end, and what the clinician says before the first dose shapes that expectation.”
“The score is a way into the first conversation: what does this person expect from getting better, and how does that change the first sessions?”
“Before applying a phase III result to your client, read what happened between screening and randomisation: a placebo run-in is the selection step the EMA names as limiting generalizability to clinical practice.”
“The sham arm lost 6.01 HDRS17 points in eight weeks – a figure to keep in mind when a client says the device is working.”
“The statement treats the patient's expectation of what deprescribing will bring as something clinicians should ask about directly.”