PSYREFLECT

Issue #79

October 5, 2026

#1Research

One tocilizumab infusion for depression that antidepressants had not moved

“For the client who has tried everything, persistent fatigue and bodily heaviness may be a prompt to ask about inflammation rather than to change the antidepressant again.”

depressioninflammationinterleukin 6tocilizumab
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#2Research

Placebo arms in acute schizophrenia trials improve, plateau and sometimes worsen

“In 6 of the 48 placebo arms, the PANSS Total score ended above its baseline value.”

schizophreniaplacebo responsenoceboPANSS
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#3Tool

Compassion focused therapy and prolonged exposure compared in 41 adults with complex PTSD

“In this trial, symptom reduction in complex PTSD did not differ between CFT and prolonged exposure, so the choice can rest on what the client can tolerate and is ready for.”

complex PTSDcompassion focused therapyprolonged exposureshame
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#4Industry

Medicare now lets clinicians bill for antidepressant tapering, and leaves the taper itself undefined

“CMS has agreed to pay for the taper, but it names no protocol for it. The clinician still has to write the plan.”

deprescribingantidepressant taperingMedicarecare management
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#5Industry

German group basic care grows fast and its regulator cannot say why

“G-BA's own reading of its figures: the descriptive analyses cannot show whether basic group care leads patients into group therapy.”

group psychotherapyGPGVGermanyG-BA
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#6Resource

A Russian ethics code tells the client before session one that online therapy may leak

“Before the first online session the therapist tells the client that confidentiality cannot be guaranteed at the in-person level, and agrees in advance who bears the cost of a technical failure.”

professional ethicsonline therapyconfidentialityinformed consent
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