PSYREFLECT

Issue #77

September 28, 2026

#1Research

When the Reconsolidation Window Opens Onto Nothing

“The interventions at day two produced no robust group differences on behavioral, self-report, or EEG measures.”

memory reconsolidationdepressionlearned helplessnessregistered report
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#2Research

A Drug That Helps Extinction Stick and Still Loses to Relapse

“NaBu facilitated later retrieval of extinction memory after seven days... but it did not prevent return of fear during a subsequent reinstatement test.”

fear extinctionreconsolidationreturn of fearHDAC inhibitor
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#3Tool

A Biomarker for Who Exposure Will Actually Work On

“COreactivity could be used as a screening tool to determine whether an individual may be a good candidate for CET or a retrieval-extinction-based approach.”

cue exposure therapyretrieval-extinctionalcohol use disorderbiomarker
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#4Industry

Watching Memory Get Rewritten Overnight, From the Wrist

“Advances in computer technology have enabled the development of widely accessible wearable devices that record objective parameters of patient activity and physiological functions.”

PTSDsleep disordersmemory reconsolidationdigital health
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#5Industry

Rescripting a Memory Works Better When You Wake It Up First

“Integrating ImRS with post-retrieval extinction may offer a novel therapeutic pathway for reducing fear relapse.”

imagery rescriptingmemory reconsolidationfear generalizationreinstatement
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#6Resource

Five Studies Are the Entire Field of TMS-Plus-Reconsolidation

“Current human evidence suggests that TMS can modulate postreactivation memory outcomes in ways that are, in some cases, compatible with a reconsolidation framework.”

transcranial magnetic stimulationmemory reconsolidationsystematic reviewfear memory
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