September 24, 2026
“Switched off olanzapine for weight gain, patients on cariprazine lost 0.82 kg more than those on aripiprazole over 12 weeks – a real difference, not a clear winner.”
“Weight loss did not track with symptom or metabolic improvement on the ketogenic diet – blood ketone level did, for both pre-diabetic markers and depression.”
“The guideline in force since January 2025 tells a psychiatrist how to test for metabolic syndrome; a 2024 literature review is what tells one how to treat it.”
“The trials that cleared GLP-1 drugs of a suicide signal excluded almost exactly the patients now being prescribed them for a psychiatric metabolic burden.”
“The measurement that took one visit had the highest compliance on the Lester chart; the one that needed six had the lowest.”
“A private family foundation, not a professional society, built the only free, accredited course on the metabolic theory of mental illness.”