August 20, 2026
“The lesion map earns its keep at the dementia end of the spectrum and goes quiet exactly where an early marker would be worth having.”
“A cognitive score moved by three and a half points while daily function only held level and no change in quality of life was reported, and that gap is not a pharmacological problem.”
“This trial has no objective sleep outcome at all: the registered actigraphy was usable in 22.3% of dyads at 8 months, and every reported number came from the unmasked family carer.”
“Eligibility, not effect size, decides the national arithmetic: 1.03 million people can receive the drug, 6.16 million can receive the care.”
“The first antipsychotic course in dementia runs to a model-adjusted median of seven months in a system whose guidance is written in weeks.”
“The manual is a content base, not a stand-alone intervention: the largest iSupport trial to date found no separation from usual care when carers were left to work through it alone.”