June 15, 2026
“A clear postpartum depression screen does not rule out a parent in sustained burnout whose toddler is already showing the behavioral signal.”
“Alcohol dependence does not simply weaken the reward circuit – it makes the striatum too specialised and the insula too diffuse, a redistribution anchored to dopamine and glutamate receptor maps.”
“The reliable psychedelic signature is not the brain dissolving into noise – it is a specific, directional binding of high-level association networks to raw sensory cortex, with the thalamus and striatum joining in.”
“Mindfulness-based treatment helped patients with OCD, yet measured mindfulness did not change and did not explain the gains; the work was done by a shift in how imagined possibilities were treated as real.”
“The four-factor model of cannabis craving did not survive the data; what remained was a single, cleaner number a clinician can actually track.”
“The automated grader agreed with the clinician consensus at a reliability of 0.81 – marginally higher than the clinicians agreed among themselves, which is what makes scoring thousands of crisis conversations feasible.”